800 Dermoscopic findings and histopathological correlation in large cell acanthoma

Large cell acanthoma (LCA) is a benign epidermal tumor that presents with pigmented hyperkeratotic patch well-demarcated boundaries in sun-exposed areas. Since various tumors present overlapping clinical and histopathological features, additional methods to differentiate them would be of great significance. Although there are numerous data on the dermoscopic findings other comparable tumors, lack features LCA. Therefore, this study aimed identify distinct LCA describe dermoscopic-histopathological correlation. Dermoscopic evaluation was conducted 33 lesions were histopathologically diagnosed Common included yellow opaque homogeneous background (97.0%), absence vascular structures (87.9%), brown dots (60.6%), moth-eaten border (57.6%), follicular openings (45.5%). Other observed prominent skin markings (42.4%), short white streaks (39.4%), white-to-yellow surface scales (27.3%), negative pigment network (18.2%), pseudonetwork linear irregular vessels (12.1%). Regarding correlation, corresponded compact uniform hyperkeratosis, small aggregates pigments basal layer, structural invagination above infundibulum without keratotic plugs. Dermoscopy significantly aids distinction Yellow background, dots, common less common, distinguishing rare tumors.